Clinical characteristics differed by neupathologies comfirmed by autopsy among Lead Investigator: Jie Zhang Institution : Zhongshan Hospital, Fudan university E-Mail : zhangjay@zoho.com Proposal ID : 723 Proposal Description: My primary goal of this anlysis is to examine the impacts of dementia neuropathologies on neuropsyhcological performance among cognitively normal elderly. Addictionally, I intend to investigate whether the impacts of dementia neuropathologies on neuropsyhcological performance are modified by APOE 4 status or sex.